Wario Land 3 (GBC, 2000)
Ikachan (PC, 2000)
Blaster Master: Blasting Again/Blaster Master (PS1, 2000)
Blaster Master: Enemy Below (GBC, 2000)

Banjo-Tooie (N64 2000) - 3D, Collectathon

​The Legend of Zelda: Majora's Mask (N64, 2000)

Vagrant Story (PS1, 2000)?
Medievil 2 (PS1, 2000)?
Sorcerian: Disciples of Seven Star Sorcery (DC)(Untranslated)?
Might and Magic VIII (PC, 2000)? 
Bouken Jidai Katsugeki: Goemon (PS2, 2000)(Untranslated)? 

Outliers: 

Mega Man Legends 2 (PS1, 2000)

Deus Ex (PC, 2000) - 3D ARPG/Stealth/FPS Hybrid
Spyro: Year of the Dragon/Spyro 3 (PS1, 2000)

Spider-Man (GBC, 2000)
Armored Core 2 (PS2, 2000)?
Paper Mario (N64, 2000)?
Nox (PC) 
Dark Cloud (PS2, 2000)?
Daikatana (GBC, 2000) 
Tenchu 2: Birth of the Stealth Assassins (PS1, 2000)? 
"Tales of Destiny II"/Tales of Eternia (PS1, 2000) 
Spider-Man (PS1/PC, 2000) 
Napple Tale: Arsia in Daydream (DC, 2000)(Untranslated)? 
Summoner (PC) - no platforming
Siege of Avalon (PC, 2000) - no platforming